Lawrie W Powell Selected Research

Hemochromatosis (Bronze Diabetes)

1/2022	Arthritis Prediction of Advanced Hepatic Fibrosis in HFE Hemochromatosis.
1/2021	Utility and limitations of Hepascore and transient elastography to detect advanced hepatic fibrosis in HFE hemochromatosis.
1/2021	Utility of Serum Biomarker Indices for Staging of Hepatic Fibrosis Before and After Venesection in Patients With Hemochromatosis Caused by Variants in HFE.
11/2020	Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels.
1/2020	Regression of Fibrosis Stage With Treatment Reduces Long-Term Risk of Liver Cancer in Patients With Hemochromatosis Caused by Mutation in HFE.
12/2019	Utility of hepatic or total body iron burden in the assessment of advanced hepatic fibrosis in HFE hemochromatosis.
1/2018	Haemochromatosis: a clinical update for the practising physician.
12/2017	Reduction of body iron in HFE-related haemochromatosis and moderate iron overload (Mi-Iron): a multicentre, participant-blinded, randomised controlled trial.
4/2017	HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women.
1/2017	Serum ferritin concentration predicts hepatic fibrosis better than hepatic iron concentration in human HFE-Haemochromatosis.

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Lawrie W Powell Research Topics

Disease

42	Hemochromatosis (Bronze Diabetes) 01/2022 - 02/2002
28	Fibrosis (Cirrhosis) 01/2022 - 02/2002
17	Iron Overload 11/2020 - 03/2002
7	Liver Diseases (Liver Disease) 12/2013 - 04/2003
5	Arthritis (Polyarthritis) 01/2022 - 01/2008
3	Hyperferritinemia 08/2018 - 12/2017
3	Fatigue 08/2015 - 01/2008
3	Hepatocellular Carcinoma (Hepatoma) 01/2008 - 03/2002
2	Fatty Liver 08/2018 - 10/2009
2	Insulin Resistance 05/2014 - 01/2012
2	Inflammation (Inflammations) 03/2014 - 05/2008
2	Diabetes Mellitus 09/2010 - 04/2002
2	Inborn Genetic Diseases (Disease, Hereditary) 02/2010 - 05/2008
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2008 - 04/2002
1	Liver Neoplasms (Liver Cancer) 01/2020
1	Reperfusion Injury 01/2018
1	Gilbert Disease 01/2018
1	Hyperbilirubinemia 01/2018
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2018
1	type 2 Rhizomelic chondrodysplasia punctata 08/2015
1	Obesity 05/2014
1	Non-alcoholic Fatty Liver Disease 01/2012
1	Hepatomegaly 09/2010
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 10/2009
1	Autoimmune Hepatitis 10/2009
1	Portal Hypertension 10/2009
1	Hepatitis 10/2009
1	Thalassemia 09/2009
1	Joint Diseases (Joint Disease) 01/2008
1	Siderosis 06/2004
1	Chronic Hepatitis C 04/2003
1	Hepatitis C 04/2003
1	Coronary Disease (Coronary Heart Disease) 10/2002
1	Cardiomyopathies (Cardiomyopathy) 04/2002

Drug/Important Bio-Agent (IBA)

42	IronIBA 01/2021 - 02/2002
14	Ferritins (Ferritin)IBA 01/2021 - 06/2004
6	Transferrin (beta 2 Transferrin)IBA 01/2018 - 03/2002
5	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022 - 02/2009
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 02/2009
3	HepcidinsIBA 08/2016 - 02/2003
2	AcyltransferasesIBA 11/2020 - 08/2015
2	Hemochromatosis ProteinIBA 01/2018 - 04/2015
2	Hormones (Hormone)IBA 08/2016 - 05/2007
2	Cysteine (L-Cysteine)FDA Link 03/2016 - 09/2002
2	Tyrosine (L-Tyrosine)FDA Link 03/2016 - 09/2002
2	DNA (Deoxyribonucleic Acid)IBA 08/2015 - 12/2013
2	Interleukin-10 (Interleukin 10)IBA 12/2013 - 04/2003
2	metal transporting protein 1 (ferroportin)IBA 05/2007 - 07/2002
2	Dietary IronIBA 06/2003 - 10/2002
1	TransferasesIBA 01/2021
1	Alanine Transaminase (SGPT)IBA 08/2018
1	BilirubinIBA 01/2018
1	Indicators and Reagents (Reagents)IBA 01/2017
1	F2-Isoprostanes (F2 Isoprostanes)IBA 08/2015
1	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 08/2015
1	Small Interfering RNA (siRNA)IBA 08/2015
1	InflammasomesIBA 05/2014
1	Nonesterified Fatty Acids (NEFA)IBA 05/2014
1	Transforming Growth Factor beta (TGF-beta)IBA 12/2013
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 12/2013
1	Toll-Like Receptor 4IBA 12/2013
1	DNA Glycosylases (DNA Glycosylase)IBA 12/2013
1	Transforming Growth Factors (Transforming Growth Factor)IBA 12/2013
1	CC ChemokinesIBA 12/2013
1	LipidsIBA 01/2012
1	CholesterolIBA 01/2012
1	Deferasirox FDA Link 11/2010
1	EnzymesIBA 09/2010
1	Chelating AgentsIBA 09/2009
1	Collagen Type IV (Type IV Collagen)IBA 02/2009
1	Hyaluronic Acid (Hyaluronan)IBA 02/2009
1	AntioxidantsIBA 05/2008
1	Transaminases (Aminotransferases)IBA 01/2008
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2003
1	Messenger RNA (mRNA)IBA 04/2003
1	CytokinesIBA 04/2003
1	Interferon-gamma (Interferon, gamma)IBA 04/2003
1	RNA (Ribonucleic Acid)IBA 02/2003
1	Peptides (Polypeptides)IBA 02/2003
1	Amino Acids FDA Link 09/2002
1	Carrier Proteins (Binding Protein)IBA 07/2002
1	Transferrin Receptors (Transferrin Receptor)IBA 07/2002
1	Tumor Suppressor Protein p14ARF (p14ARF)IBA 03/2002
1	Cyclin-Dependent Kinase Inhibitor p16IBA 03/2002

Therapy/Procedure

6	Therapeutics 03/2016 - 04/2002
2	Transplantation 10/2009 - 06/2004
1	Aftercare (After-Treatment) 01/2020
1	Liver Transplantation 06/2004